Congenic Mice

B10.BR-H2K2H2-T18a/SgSnJArc

Product code BR
JAX stock number 000465
Strain Description Congenic.Created by transferring through backcrossing the H2Kk of the inbred strain C57BR onto the C57BL/10ScSn.
Coat Colour Black (a/a)
MHC Haplotype H2Kk
  • Used in research for CD antigens, antigen receptors and histocompatibility markers.
  • Good breeding performance (refer to C57Bl/10ScSn).
  • Fecundity lower than C57BL/10ScSn but can have large litters.
  • Corneal opacities may be observed from two weeks of age.
  • White spotting may be observed in pigmentation.
  • See www.jax.org  for more strain information.
  • These mice are sold subject to The Jackson Laboratory’s Conditions of Use and also the Australian Patent Number (2004268530). Information regarding conditions of use is available at: http://jaxmice.jax.org/cou/index.html.

B10BR

____________________________________________________________________________________________________

B6.A-Dysfprmd/GeneJArc

Product code BLA
JAX stock number 012767
Strain Description Congenic
Coat Colour Black
  • Mice contain the progressive muscular dystrophy (prmd) allele from the A/J inbred strain that was introgressed to the C57BL/6 genetic background.
  • The Jain Foundation is sponsoring the maintenance of the colony at the Animal Resources Centre for research into dysferlin deficiency.
  • Animals are free of charge for research approved by the Jain Foundation. ARC prices for animal shippers and transport apply to all orders.
  • The Jain Foundation will be informed of any BLA/Js that the ARC supplies.
  • See www.jax.org for more strain information.

JAIN Founndation

____________________________________________________________________________________________________

B6.SJL-PtprcaPep3b/BoyJArc

Product code PTP
Strain Description CongenicCreated by transferring through backcrossing the Ptprca and Pep3b genes of the inbred strain SJL/J onto the C57BL/6 background.
Coat Colour Black (a/a)
MHC Haplotype H2Kb
Complement Factor C5 normal
  •  Poor breeding performance (refer to C57Bl/6J).
  • Confusion has occurred over the years due to changes in nomenclature of the T-Lymphocyte cell surface antigen CD45.
  • Ptprca (protein-tyrosine phosphatase, receptor type c) was the gene symbol designated to the CD45 antigen because of its homology with human placental protein-tyrosine phosphatase 1B. Ptprca is one of a family of protein-tyrosine   phosphatase genes involved with the regulation of cell growth.
  • Congenital abnormalities include microphthalmia, corneal opacities, anophthalmia and hydrocephalus.
  • Susceptible to imperforate vaginas, divided septums and mucometra.

Ptprca